CHARLES Sturt University expects around 100 full-time equivalent positions to go in the next phase of its cost-cutting program.
It anticipates the job losses will come predominantly from "voluntary separations", for which applications will close in a fortnight.
CSU is in the midst of what it calls its Sustainable Futures program, which aims to reduce the university's deficit to approximately $22 million in the 2020 financial year and put CSU on the path to a balanced budget by the end of the 2021 financial year.
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The university put out a statement on Wednesday saying staff had been briefed about the second phase of Sustainable Futures, in which academic staff who primarily teach in or are aligned to the discipline areas affected by the university's course changes will be given the opportunity to apply for a voluntary separation.
"Some faculty-based technical staff will also be eligible to apply," the statement from acting vice-chancellor Professor John Germov said.
The university says applications for voluntary separations will close on Friday, October 16 and applicants will receive a decision from CSU "soon after that date".
"When we first launched the Sustainable Futures program, the university received strong feedback from staff they would like us to offer voluntary separations," Professor Germov said in the statement.
"We have worked collaboratively with our unions to make this a reality.
"These voluntary separations will be balanced with eligibility criteria so that the university can maintain the appropriate workforce to continue to deliver quality teaching for our students and important research outcomes for our regions.
"We have worked hard to identify and implement changes to make savings across our operations but, unfortunately, we cannot avoid job losses.
"While these are voluntary separations we appreciate this is not an easy process for any of our staff, and our main priority at this time is to provide support to those affected."
CSU announced a number of changes to its course offering earlier this year, including the consolidation of six Bachelor of Business degrees into one (that will offer specialisations) at its Bathurst campus.
CSU said at the time that only four per cent of current students were enrolled in a course approved for change.