The male driver of the truck, believed to be in his 30s, was treated at the scene by NSW Ambulance paramedics for head injuries.
The truck's passenger, also a male in his 30s, was treated for minor injuries.
Both were conveyed to Orange Hospital in stable conditions where they remain.
The Castlereagh Highway was closed in both directions as a salvage operation continued however a diversion for eastbound traffic was made available through Sofala.
Our journalists work hard to provide local, up-to-date news to the community. This is how you can access our trusted content: